VAC14 and CD209

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VAC14	CD209
Description		VAC14 component of PIKFYVE complex	CD209 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell
	Molecular Function	Protein Binding Signaling Receptor Activity	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion
Pathways		Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane	CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pulse pressure ( 28135244)	Blood protein levels ( 30072576 29875488)
Interacting Genes		53 interacting genes: ACSS1 APP ASB13 BCL2L1 BHLHE40 C11orf54 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK DDAH2 FNDC3B GALT GINS3 HNRNPLL JMJD7 KRTAP19-5 KRTAP19-7 KYAT1 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 NTAQ1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TP53BP1 ZCWPW1 ZNF34	7 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14
Entrez ID		55697	30835
HPRD ID		07660	05241
Ensembl ID		ENSG00000103043	ENSG00000090659
Uniprot IDs		Q08AM6	B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12
PDB IDs			1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV
Enriched GO Terms of Interacting Partners?
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