SRSF4 and RNPS1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SRSF4	RNPS1
Description		serine and arginine rich splicing factor 4	RNA binding protein with serine rich domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Insulin MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Artenimol
Diseases
GWAS		Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		23 interacting genes: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF1 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B ZDHHC17	34 interacting genes: CHERP CLK2 DVL2 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKTR PIN1 PNN PRPF38A RBM8A SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRSF1 SRSF11 SRSF4 SRSF6 TAF2 TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YWHAB YWHAG ZBTB14 ZNF473 ZNF490
Entrez ID		6429	10921
HPRD ID		09052	07341
Ensembl ID		ENSG00000116350	ENSG00000205937
Uniprot IDs		Q08170	D3DU92 H3BMS0 Q15287
PDB IDs			4A8X
Enriched GO Terms of Interacting Partners?
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