RNPS1 and SRSF1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (biochemical, two hybrid)

		RNPS1	SRSF1
Description		RNA binding protein with serine rich domain 1	serine and arginine rich splicing factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS
Interacting Genes		34 interacting genes: CHERP CLK2 DVL2 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKTR PIN1 PNN PRPF38A RBM8A SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRSF1 SRSF11 SRSF4 SRSF6 TAF2 TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YWHAB YWHAG ZBTB14 ZNF473 ZNF490	40 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		10921	6426
HPRD ID		07341	02887
Ensembl ID		ENSG00000205937	ENSG00000136450
Uniprot IDs		D3DU92 H3BMS0 Q15287	Q07955 Q59FA2
PDB IDs		4A8X	1X4A 2M7S 2M8D 2O3D 3BEG 4C0O
Enriched GO Terms of Interacting Partners?
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