SRSF3 and CHD1

Number of citations of the paper that reports this interaction (PubMedID 12890497)
23

Data Source:
HPRD (in vitro, two hybrid)

		SRSF3	CHD1
Description		serine and arginine rich splicing factor 3	chromodomain helicase DNA binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding Methylated Histone Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Covalent Chromatin Modification DNA Duplex Unwinding Positive Regulation By Host Of Viral Transcription
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Estrogen-dependent gene expression
Drugs			Epirubicin
Diseases
GWAS		Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Basophil percentage of white cells ( 27863252) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Periodontitis (Mean PAL) ( 24024966) Renal sinus fat ( 22044751)
Interacting Genes		21 interacting genes: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	9 interacting genes: BCLAF1 H3-3A H3-4 HDAC1 NCOR1 SAFB SPP1 SRSF3 SSRP1
Entrez ID		6428	1105
HPRD ID		04530	03668
Ensembl ID		ENSG00000112081	ENSG00000153922
Uniprot IDs		B2R6F3 P84103	B3KT33 O14646
PDB IDs		2I2Y 2I38	2B2T 2B2U 2B2V 2B2W 2B2Y 2N39 4B4C 4NW2 4O42 5AFW
Enriched GO Terms of Interacting Partners?
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