SRSF3 and NXF1

Number of citations of the paper that reports this interaction (PubMedID 17036044)
67

Data Source:
HPRD (in vitro)

		SRSF3	NXF1
Description		serine and arginine rich splicing factor 3	nuclear RNA export factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear Inclusion Body
	Molecular Function	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	54 interacting genes: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 LUZP4 MAGOH MAP1A MAP1B MARK2 MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRPK2 SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2
Entrez ID		6428	10482
HPRD ID		04530	04035
Ensembl ID		ENSG00000112081	ENSG00000162231
Uniprot IDs		B2R6F3 P84103	Q59E96 Q9UBU9
PDB IDs		2I2Y 2I38	1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U
Enriched GO Terms of Interacting Partners?
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