CXCL11 and CXCR3

Number of citations of the paper that reports this interaction (PubMedID 9625760)
202

Data Source:
HPRD (in vivo, in vitro)

		CXCL11	CXCR3
Description		C-X-C motif chemokine ligand 11	C-X-C motif chemokine receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell	Cell Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding Identical Protein Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Neutrophil Chemotaxis Leukocyte Chemotaxis Regulation Of Cell Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Angiogenesis Regulation Of Leukocyte Migration Apoptotic Process Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration T Cell Chemotaxis Calcium-mediated Signaling Regulation Of Cell Adhesion Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		6 interacting genes: CCR3 CXCR3 DPP4 LRRK2 MTUS2 SMARCB1	6 interacting genes: CXCL10 CXCL11 CXCL13 CXCL9 FATE1 PF4
Entrez ID		6373	2833
HPRD ID		05329	02936
Ensembl ID		ENSG00000169248	ENSG00000186810
Uniprot IDs		O14625	P49682
PDB IDs		1RJT
Enriched GO Terms of Interacting Partners?
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