CXCR3 and CXCL9

Number of citations of the paper that reports this interaction (PubMedID 12782716)
162

Data Source:
HPRD (in vitro, in vivo)

		CXCR3	CXCL9
Description		C-X-C motif chemokine receptor 3	C-X-C motif chemokine ligand 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Extracellular Space Cell External Side Of Plasma Membrane
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding Identical Protein Binding	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Angiogenesis Regulation Of Leukocyte Migration Apoptotic Process Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration T Cell Chemotaxis Calcium-mediated Signaling Regulation Of Cell Adhesion Cell Chemotaxis Chemokine-mediated Signaling Pathway	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Leukocyte Chemotaxis Regulation Of Cell Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		6 interacting genes: CXCL10 CXCL11 CXCL13 CXCL9 FATE1 PF4	10 interacting genes: BMF CCR3 CXCR3 DPP4 FBXO7 KASH5 PAX8 PTPN5 SFTPC SYNE4
Entrez ID		2833	4283
HPRD ID		02936	03416
Ensembl ID		ENSG00000186810	ENSG00000138755
Uniprot IDs		P49682	Q07325
PDB IDs
Enriched GO Terms of Interacting Partners?
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