RPGR and SMC1A

Number of citations of the paper that reports this interaction (PubMedID 16043481)
65

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		RPGR	SMC1A
Description		retinitis pigmentosa GTPase regulator	structural maintenance of chromosomes 1A
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Mitotic Spindle Pole
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Chromatin Binding RNA Binding Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Response To Stimulus Cilium Assembly	Mitotic Sister Chromatid Segregation DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Response To Radiation Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Response To DNA Damage Checkpoint Signaling Regulation Of Mitotic Spindle Assembly
Pathways			Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)	Cornelia de Lange syndrome (CdLS)
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	17 interacting genes: ATM BLM BRCA1 ESR1 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3
Entrez ID		6103	8243
HPRD ID		02425	02077
Ensembl ID		ENSG00000156313	ENSG00000072501
Uniprot IDs		Q92834	A0A384MR33 G8JLG1 Q14683 Q68EN4
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?