DHPS and NIF3L1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DHPS	NIF3L1
Description		deoxyhypusine synthase	NGG1 interacting factor 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding	Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS			Triptolide cytotoxicity ( 26121980)
Interacting Genes		13 interacting genes: BRCA1 EIF5A EIF5A2 NIF3L1 NTAQ1 NUDT18 PTPRH RAB27B REL RPL9 UPF1 VASH1 ZNF138	67 interacting genes: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PNMA1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1
Entrez ID		1725	60491
HPRD ID		02969	10424
Ensembl ID		ENSG00000095059	ENSG00000196290
Uniprot IDs		A0A024R7D0 A0A024R7E9 P49366	A0A024R3V5 A0A024R3V7 Q9GZT8
PDB IDs		1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?
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