MYOZ1 and LDB3

Number of citations of the paper that reports this interaction (PubMedID 11842093)
44

Data Source:
HPRD (in vivo, two hybrid)

		MYOZ1	LDB3
Description		myozenin 1	LIM domain binding 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Actin Cytoskeleton Z Disc Pseudopodium	Stress Fiber Cytoskeleton Adherens Junction Z Disc Pseudopodium Filamentous Actin Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding FATZ Binding	Actin Binding Protein Kinase C Binding Protein Binding Cytoskeletal Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Heart Development Actin Cytoskeleton Organization Sarcomere Organization Muscle Structure Development
Pathways
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Atrial fibrillation ( 30061737)	Heel bone mineral density ( 30598549) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		14 interacting genes: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC GRB2 LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63	7 interacting genes: ACTN2 ANKRD2 MYOZ1 MYOZ2 MYOZ3 TFCP2 TP53
Entrez ID		58529	11155
HPRD ID		05725	16172
Ensembl ID		ENSG00000177791	ENSG00000122367
Uniprot IDs		Q9NP98	A0A0S2Z501 A0A0S2Z530 O75112
PDB IDs			1RGW 4YDP
Enriched GO Terms of Interacting Partners?
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