LDB3 and MYOZ1

Number of citations of the paper that reports this interaction (PubMedID 11842093)
44

Data Source:
HPRD (in vivo, two hybrid)

		LDB3	MYOZ1
Description		LIM domain binding 3	myozenin 1
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoskeleton Adherens Junction Z Disc Pseudopodium Filamentous Actin Perinuclear Region Of Cytoplasm	Nucleus Actin Cytoskeleton Z Disc Pseudopodium
	Molecular Function	Actin Binding Protein Kinase C Binding Protein Binding Cytoskeletal Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding FATZ Binding
	Biological Process	Heart Development Actin Cytoskeleton Organization Sarcomere Organization Muscle Structure Development	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Heel bone mineral density ( 30598549) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Atrial fibrillation ( 30061737)
Interacting Genes		7 interacting genes: ACTN2 ANKRD2 MYOZ1 MYOZ2 MYOZ3 TFCP2 TP53	14 interacting genes: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC GRB2 LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63
Entrez ID		11155	58529
HPRD ID		16172	05725
Ensembl ID		ENSG00000122367	ENSG00000177791
Uniprot IDs		A0A0S2Z501 A0A0S2Z530 O75112	Q9NP98
PDB IDs		1RGW 4YDP
Enriched GO Terms of Interacting Partners?
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