NCOA5 and KHDRBS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NCOA5	KHDRBS2
Description		nuclear receptor coactivator 5	KH RNA binding domain containing, signal transduction associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Actin Cytoskeleton	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding RNA Binding Protein Binding	RNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Identical Protein Binding
	Biological Process	Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs		(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL
Diseases
GWAS		Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		8 interacting genes: CDC37 HTATIP2 KHDRBS2 KHDRBS3 NR1D2 NTAQ1 SYT16 TSC22D1	34 interacting genes: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRAP2 GRB2 HBZ HNRNPK HNRNPLL KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM3 RBMX SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF688
Entrez ID		57727	202559
HPRD ID		14813	13775
Ensembl ID		ENSG00000124160	ENSG00000112232
Uniprot IDs		Q9HCD5	Q5VWX1
PDB IDs		1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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