KHDRBS2 and CATSPER1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KHDRBS2	CATSPER1
Description		KH RNA binding domain containing, signal transduction associated 2	cation channel sperm associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Plasma Membrane Motile Cilium CatSper Complex
	Molecular Function	RNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Identical Protein Binding	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding
	Biological Process	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Calcium Ion Transport Multicellular Organism Development Spermatogenesis Cell Differentiation Flagellated Sperm Motility Response To Progesterone Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Transmembrane Transport
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Sperm Motility And Taxes
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)
Interacting Genes		34 interacting genes: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRAP2 GRB2 HBZ HNRNPK HNRNPLL KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM3 RBMX SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF688	33 interacting genes: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NLA PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6
Entrez ID		202559	117144
HPRD ID		13775	09396
Ensembl ID		ENSG00000112232	ENSG00000175294
Uniprot IDs		Q5VWX1	Q8NEC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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