GATAD2B and RPGRIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GATAD2B	RPGRIP1
Description		GATA zinc finger domain containing 2B	RPGR interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm NuRD Complex Nuclear Speck Protein-containing Complex	Axoneme Photoreceptor Connecting Cilium
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Nucleosomal DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II ATP-dependent Chromatin Remodeling	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye Neural Precursor Cell Proliferation
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases			Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Age at first birth ( 27798627) Chronotype ( 30696823) Empathy quotient ( 29527006) General cognitive ability ( 29844566) Height ( 31562340) Lentiform nucleus volume ( 22903471) Number of children ever born ( 27798627)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Height ( 31562340) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		20 interacting genes: CALCOCO2 CEP70 GOLGA2 H2AC20 H2BC21 H3C1 H4C1 KAT2B MBD2 MBD3 MTNR1A PRKAB2 RBPMS RPGRIP1 SMAD2 SUMO2 TEX11 TRAF1 TRIM27 USHBP1	26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688
Entrez ID		57459	57096
HPRD ID		15094	05673
Ensembl ID		ENSG00000143614	ENSG00000092200
Uniprot IDs		Q8WXI9	Q96KN7
PDB IDs			4QAM
Enriched GO Terms of Interacting Partners?
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