THAP11 and VPS52

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		THAP11	VPS52
Description		THAP domain containing 11	VPS52 subunit of GARP complex
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Cytosol Intercellular Bridge	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Rab GTPase Binding Syntaxin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		18 interacting genes: C9orf16 CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN LRRC45 MCPH1 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2
Entrez ID		57215	6293
HPRD ID		11629	09142
Ensembl ID		ENSG00000168286	ENSG00000223501
Uniprot IDs		Q96EK4	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs		2LAU 5AJS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?