VPS52 and NOP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS52	NOP2
Description		VPS52 subunit of GARP complex	NOP2 nucleolar protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex	Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	RNA Binding Protein Binding RRNA (cytosine-C5-)-methyltransferase Activity
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	Ribosomal Large Subunit Assembly Maturation Of LSU-rRNA RNA Methylation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation RRNA Base Methylation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Retrograde transport at the Trans-Golgi-Network	rRNA modification in the nucleus and cytosol TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	10 interacting genes: CDCA7L CEP70 KPNA6 MCRS1 MT1F NPM1 PTPRJ SUMO2 UBE2I VPS52
Entrez ID		6293	4839
HPRD ID		09142	01244
Ensembl ID		ENSG00000223501	ENSG00000111641
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	P46087
PDB IDs
Enriched GO Terms of Interacting Partners?
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