CTNNBIP1 and CTNNA2

Number of citations of the paper that reports this interaction (PubMedID 16325583)
375

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		CTNNBIP1	CTNNA2
Description		catenin beta interacting protein 1	catenin alpha 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex	Nucleus Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Basolateral Plasma Membrane Lamellipodium Axon Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Presynaptic Active Zone Cytoplasmic Component Extrinsic Component Of Presynaptic Membrane Extrinsic Component Of Postsynaptic Membrane Postsynaptic Density, Intracellular Component
	Molecular Function	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Complex Assembly Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation	Cytoskeleton Organization Axonogenesis Regulation Of Neuron Projection Development Radial Glia Guided Migration Of Purkinje Cell Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendrite Morphogenesis Brain Morphogenesis Positive Regulation Of Muscle Cell Differentiation Regulation Of Synapse Structural Plasticity Prepulse Inhibition Cell-cell Adhesion Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Neuron Migration
Pathways		Deactivation of the beta-catenin transactivating complex	Myogenesis Myogenesis
Drugs
Diseases
GWAS		Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Alcohol consumption ( 28937693) Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767) Alzheimer's disease (cognitive decline) ( 23535033) Bipolar disorder ( 19416921) Body mass index ( 26426971 25673413) Bone mineral density (femoral neck) ( 26911590) Breast cancer ( 25824743) Cerebral microbleeds ( 31209788) Cerebrospinal fluid clusterin levels ( 26545630) Cleft palate ( 30452639) Cognitive function ( 25644384) Contrast sensitivity ( 24152035) Mild influenza (H1N1) infection ( 26379185) Multisite chronic pain ( 31194737) Orthostatic hypotension ( 24124408) Protein quantitative trait loci ( 18464913) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to lurasidone in schizophrenia ( 29730043) Survival in pancreatic cancer ( 28470677)
Interacting Genes		11 interacting genes: BEND5 CTNNA2 CTNNB1 EMD INCA1 JUP KRTAP10-3 KRTAP10-7 REL TCF7L2 USHBP1	3 interacting genes: CTNNBIP1 PTPN14 TOMM70
Entrez ID		56998	1496
HPRD ID		09677	00228
Ensembl ID		ENSG00000178585	ENSG00000066032
Uniprot IDs		A0A024R4D7 Q9NSA3	F6KRI5 P26232 Q49AD3
PDB IDs		1LUJ 1M1E 1T08	6DUW
Enriched GO Terms of Interacting Partners?
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