CTNNA2 and PTPN14

Number of citations of the paper that reports this interaction (PubMedID 12808048)
36

Data Source:
HPRD (in vitro)

		CTNNA2	PTPN14
Description		catenin alpha 2	protein tyrosine phosphatase non-receptor type 14
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Adherens Junction Actin Cytoskeleton Basolateral Plasma Membrane Lamellipodium Axon Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Presynaptic Active Zone Cytoplasmic Component Extrinsic Component Of Presynaptic Membrane Extrinsic Component Of Postsynaptic Membrane Postsynaptic Density, Intracellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding Cadherin Binding Actin Filament Binding	Transcription Coregulator Activity Protein Tyrosine Phosphatase Activity Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	Cytoskeleton Organization Axonogenesis Regulation Of Neuron Projection Development Radial Glia Guided Migration Of Purkinje Cell Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendrite Morphogenesis Brain Morphogenesis Positive Regulation Of Muscle Cell Differentiation Regulation Of Synapse Structural Plasticity Prepulse Inhibition Cell-cell Adhesion Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Neuron Migration	Lymphangiogenesis Protein Dephosphorylation Negative Regulation Of Cell Proliferation Peptidyl-tyrosine Dephosphorylation Regulation Of Protein Export From Nucleus Cellular Response To Cytokine Stimulus Regulation Of Nucleic Acid-templated Transcription
Pathways		Myogenesis Myogenesis	Interleukin-37 signaling
Drugs
Diseases			Choanal atresia and lymphedema
GWAS		Alcohol consumption ( 28937693) Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767) Alzheimer's disease (cognitive decline) ( 23535033) Bipolar disorder ( 19416921) Body mass index ( 26426971 25673413) Bone mineral density (femoral neck) ( 26911590) Breast cancer ( 25824743) Cerebral microbleeds ( 31209788) Cerebrospinal fluid clusterin levels ( 26545630) Cleft palate ( 30452639) Cognitive function ( 25644384) Contrast sensitivity ( 24152035) Mild influenza (H1N1) infection ( 26379185) Multisite chronic pain ( 31194737) Orthostatic hypotension ( 24124408) Protein quantitative trait loci ( 18464913) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to lurasidone in schizophrenia ( 29730043) Survival in pancreatic cancer ( 28470677)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Birth weight ( 31043758) Bone mineral density (hip) ( 30172743) Estimated glomerular filtration rate ( 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Height ( 28552196 25429064 31562340) Lipid traits ( 24386095) Plasma thyroid-stimulating hormone levels ( 24722205)
Interacting Genes		3 interacting genes: CTNNBIP1 PTPN14 TOMM70	6 interacting genes: CDH1 CTNNA2 CTNNB1 JUP TJP1 YWHAG
Entrez ID		1496	5784
HPRD ID		00228	04402
Ensembl ID		ENSG00000066032	ENSG00000152104
Uniprot IDs		F6KRI5 P26232 Q49AD3	A8K6H6 Q15678
PDB IDs		6DUW	2BZL 6IWD 6JJW
Enriched GO Terms of Interacting Partners?
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