LHX9 and LDB2

Number of citations of the paper that reports this interaction (PubMedID 9880598)
39

Data Source:
HPRD (in vitro)

		LHX9	LDB2
Description		LIM homeobox 9	LIM domain binding 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Plasma Membrane Cell Leading Edge
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding
	Biological Process	Cell Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Dorsal Spinal Cord Interneuron Anterior Axon Guidance	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Multicellular Organism Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)	Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)
Interacting Genes		5 interacting genes: CWF19L2 KHK LDB2 SMAD2 SMURF1	12 interacting genes: ISL1 LHX4 LHX9 LMO3 LMO4 RASIP1 RILP RLIM SSBP2 SSBP3 SSBP4 TSNAX
Entrez ID		56956	9079
HPRD ID		07299	16022
Ensembl ID		ENSG00000143355	ENSG00000169744
Uniprot IDs		H0YL54 Q9NQ69	B7Z6D0 E9PFI4 G5E9Y7 O43679
PDB IDs		2DMQ
Enriched GO Terms of Interacting Partners?
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