RAD18 and TRIM8

  • Number of citations of the paper that reports this interaction (PubMedID 22493164)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

RAD18

TRIM8

Description RAD18 E3 ubiquitin protein ligase tripartite motif containing 8
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Feeling nervous ( 29500382)
  • Prostate cancer ( 23535732)
  • Pulse pressure ( 30578418)
  • Schizophrenia ( 25056061 30285260)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Ulcerative colitis ( 26192919)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 25 interacting genes: DZIP3 MAGEA4 MAP3K1 MAPK8 MLKL NBN PCGF6 PCNA POLK RAD51 RFC2 SHPRH SIVA1 TAX1BP1 TP53BP1 TRIM23 TRIM8 TSG101 UBC UBE2A UBE2B UBE2D2 UBE2I USP2 USP7 46 interacting genes: BRAP CBL CCNH ITSN1 MAGEC2 MKRN3 MSL2 OTUB2 PCGF5 RAD18 RC3H2 RCHY1 RNF111 RNF113A RNF138 RNF141 RNF181 RNF41 RNF7 SIAH1 SOCS1 TICAM1 TNFAIP3 TRAF5 TRIM15 TRIM2 TRIM21 TRIM24 TRIM25 TRIM39 TRIM43 TRIM47 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L6 UBE2V1 UBE2W UHRF2 USP2 USP21 USP39 USP7 XIAP
Entrez ID 56852 81603
HPRD ID 09242 06934
Ensembl ID ENSG00000070950 ENSG00000171206
Uniprot IDs Q9NS91 Q9BZR9
PDB IDs 2MRE 2MRF 2Y43 2YBF 5VF0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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