BTBD2 and BRD7

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		BTBD2	BRD7
Description		BTB domain containing 2	bromodomain containing 7
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GO Annotations	Cellular Component	P-body Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Neurogenesis	Regulation Of Transcription By RNA Polymerase II Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 27863252)	Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		28 interacting genes: BRD7 CCDC90B CDK2 COPS6 CRMP1 DPPA4 EEF1A1 ERG28 GAPDH GBP2 GDF9 IGSF21 KPNA2 PTN RBM48 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B ZYG11B	30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TP53 TRIM24
Entrez ID		55643	29117
HPRD ID		12252	12531
Ensembl ID		ENSG00000133243	ENSG00000166164
Uniprot IDs		Q9BX70	Q9NPI1
PDB IDs		3NO8	2I7K 5MQ1
Enriched GO Terms of Interacting Partners?
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