NSD3 and SPAG8

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		NSD3	SPAG8
Description		nuclear receptor binding SET domain protein 3	sperm associated antigen 8
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Blood protein levels ( 28240269)
Interacting Genes		40 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 UBE2I ZNF557	16 interacting genes: CARM1 CSTF2 DTX2 JMJD4 KDM3B KLHL32 NEDD4L NSD3 PITX1 PRMT1 PRMT2 PRMT5 RAN SIGMAR1 SNRPC UBQLN4
Entrez ID		54904	26206
HPRD ID		06155	12039
Ensembl ID		ENSG00000147548	ENSG00000137098
Uniprot IDs		Q9BZ95	A0A140VJV0 Q99932
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T
Enriched GO Terms of Interacting Partners?
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