SPAG8 and NSD3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		SPAG8	NSD3
Description		sperm associated antigen 8	nuclear receptor binding SET domain protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Transcription Coactivator Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)
	Biological Process	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)
Interacting Genes		16 interacting genes: CARM1 CSTF2 DTX2 JMJD4 KDM3B KLHL32 NEDD4L NSD3 PITX1 PRMT1 PRMT2 PRMT5 RAN SIGMAR1 SNRPC UBQLN4	40 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 UBE2I ZNF557
Entrez ID		26206	54904
HPRD ID		12039	06155
Ensembl ID		ENSG00000137098	ENSG00000147548
Uniprot IDs		A0A140VJV0 Q99932	Q9BZ95
PDB IDs			2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T
Enriched GO Terms of Interacting Partners?
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