EPS8L1 and ABI1

Number of citations of the paper that reports this interaction (PubMedID 14565974)
41

Data Source:
HPRD (in vivo)

		EPS8L1	ABI1
Description		EPS8 like 1	abl interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Ruffle Membrane Protein-containing Complex Extracellular Exosome	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Aggresome Lamellipodium Cell Junction Growth Cone SCAR Complex Filopodium Tip Extracellular Exosome
	Molecular Function	Actin Binding Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity T Cell Receptor Binding Cadherin Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Protein Tyrosine Kinase Activator Activity Cadherin Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Positive Regulation Of Ruffle Assembly	Somitogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Viral Process Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Dendrite Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: ABI1 ACTN2 CD3E SOS1 SRPK2 TERF2IP	29 interacting genes: ABL1 APBB1 CACNA1A CUL2 CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PCM1 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2
Entrez ID		54869	10006
HPRD ID		13276	04336
Ensembl ID		ENSG00000131037	ENSG00000136754
Uniprot IDs		Q8TE68	A0A0A0MRT6 B6VEX3 B6VEX4 B6VEX5 Q8IZP0
PDB IDs		2K2M 2ROL
Enriched GO Terms of Interacting Partners?
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