ABI1 and EPS8L1

Number of citations of the paper that reports this interaction (PubMedID 14565974)
41

Data Source:
HPRD (in vivo)

		ABI1	EPS8L1
Description		abl interactor 1	EPS8 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Aggresome Lamellipodium Cell Junction Growth Cone SCAR Complex Filopodium Tip Extracellular Exosome	Cytosol Plasma Membrane Ruffle Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Protein Tyrosine Kinase Activator Activity Cadherin Binding	Actin Binding Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity T Cell Receptor Binding Cadherin Binding
	Biological Process	Somitogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Viral Process Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Dendrite Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis	Rho Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Positive Regulation Of Ruffle Assembly
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: ABL1 APBB1 CACNA1A CUL2 CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PCM1 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2	6 interacting genes: ABI1 ACTN2 CD3E SOS1 SRPK2 TERF2IP
Entrez ID		10006	54869
HPRD ID		04336	13276
Ensembl ID		ENSG00000136754	ENSG00000131037
Uniprot IDs		A0A0A0MRT6 B6VEX3 B6VEX4 B6VEX5 Q8IZP0	Q8TE68
PDB IDs			2K2M 2ROL
Enriched GO Terms of Interacting Partners?
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