MAGEL2 and PCGF6

Number of citations of the paper that reports this interaction (PubMedID 25590999)
15

Data Source:
BioGRID (two hybrid)

		MAGEL2	PCGF6
Description		MAGE family member L2	polycomb group ring finger 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome Early Endosome Cytosol Retromer Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition
Pathways			Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		4 interacting genes: IRS4 PCGF6 RNF41 VPS52	22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21
Entrez ID		54551	84108
HPRD ID		12008	07427
Ensembl ID		ENSG00000254585	ENSG00000156374
Uniprot IDs		Q9UJ55	Q9BYE7
PDB IDs			2DJB
Enriched GO Terms of Interacting Partners?
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