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PCGF6

Description polycomb group ring finger 6
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • PcG Protein Complex
  • PRC1 Complex
Molecular Function
  • RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • DNA Binding
  • DNA-binding Transcription Factor Activity
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Histone H2A-K119 Monoubiquitination
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Inactivation Of X Chromosome By Genetic Imprinting
  • Negative Regulation Of G0 To G1 Transition
Pathways
  • Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
  • Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes 22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21
Entrez ID 84108
HPRD ID 07427
Ensembl ID ENSG00000156374
Uniprot IDs Q9BYE7
PDB IDs 2DJB
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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