DCUN1D1 and CAND1

Number of citations of the paper that reports this interaction (PubMedID 29499133)
5

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		DCUN1D1	CAND1
Description		defective in cullin neddylation 1 domain containing 1	cullin associated and neddylation dissociated 1
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Cytosol	Ubiquitin Ligase Complex Extracellular Region Cell Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Cullin-RING Ubiquitin Ligase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding TBP-class Protein Binding
	Biological Process	Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Neddylation	Cellular Iron Ion Homeostasis SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Neutrophil Degranulation Post-translational Protein Modification Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways		Neddylation	Neutrophil degranulation Neddylation Iron uptake and transport
Drugs
Diseases
GWAS		Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)	Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Expressive vocabulary in infants ( 25226531) Hippocampal atrophy ( 19668339) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653)
Interacting Genes		25 interacting genes: ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CUL5 DAZAP2 DVL2 LAPTM5 LZTS2 MAP3K1 NEDD4 RHOA RNF11 SMAD2 TLE5 TP53BP2 TRIM39 TRIM54 UBC UBE2D3 UBE2F UBE2M VPS37B	16 interacting genes: CA9 CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 DCUN1D2 DCUN1D4 DCUN1D5 MTNR1A RBX1 SKP1 SRPK2 UBE2M
Entrez ID		54165	55832
HPRD ID		12067	06983
Ensembl ID		ENSG00000043093	ENSG00000111530
Uniprot IDs		B4DM76 C9JVE2 Q96GG9	Q86VP6
PDB IDs		3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W	1U6G 4A0C
Enriched GO Terms of Interacting Partners?
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