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PRKAG3 and PRKAA1
Number of citations of the paper that reports this interaction (PubMedID
8626596
)
60
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
PRKAG3
PRKAA1
Description
protein kinase AMP-activated non-catalytic subunit gamma 3
protein kinase AMP-activated catalytic subunit alpha 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Cytosol
Nucleotide-activated Protein Kinase Complex
Cell
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Apical Plasma Membrane
Nuclear Speck
Axon
Dendrite
Nucleotide-activated Protein Kinase Complex
Neuronal Cell Body
Molecular Function
AMP-activated Protein Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Histone Serine Kinase Activity
Protein-containing Complex Binding
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Tau Protein Binding
Tau-protein Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Biological Process
Glycogen Biosynthetic Process
Glycolytic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cell Cycle Arrest
Response To Muscle Activity Involved In Regulation Of Muscle Adaptation
Macroautophagy
Regulation Of Macroautophagy
Intracellular Signal Transduction
Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Activation Of MAPK Activity
Response To Hypoxia
Glucose Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Cell Cycle Arrest
Signal Transduction
Positive Regulation Of Cell Proliferation
Lipid Biosynthetic Process
Response To UV
Cold Acclimation
Response To Gamma Radiation
Positive Regulation Of Autophagy
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Response To Activity
Wnt Signaling Pathway
Macroautophagy
Regulation Of Macroautophagy
Fatty Acid Oxidation
Response To Caffeine
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Regulation Of Peptidyl-serine Phosphorylation
Cellular Response To Oxidative Stress
Histone-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Glucose Starvation
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Glycolytic Process
Negative Regulation Of Glucosylceramide Biosynthetic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Rhythmic Process
Positive Regulation Of Skeletal Muscle Tissue Development
Negative Regulation Of Lipid Catabolic Process
Fatty Acid Homeostasis
Regulation Of Vesicle-mediated Transport
Motor Behavior
CAMKK-AMPK Signaling Cascade
Regulation Of Stress Granule Assembly
Neuron Cellular Homeostasis
Cellular Response To Hydrogen Peroxide
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Ethanol
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Organonitrogen Compound
Cellular Response To Hypoxia
Energy Homeostasis
Response To Camptothecin
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Mitochondrial Transcription
Positive Regulation Of Cellular Protein Localization
Positive Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Tubulin Deacetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Macroautophagy
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Activation of AMPK downstream of NMDARs
Drugs
Acetylsalicylic acid
Adenosine monophosphate
ATP
Phenformin
Acetylsalicylic acid
Diseases
GWAS
HDL cholesterol (
25961943
)
Male-pattern baldness (
28196072
)
Cardia gastric cancer (
26129866
)
Gastric cancer (
22037551
26098866
26129866
31383772
)
Non-cardia gastric cancer (
26701879
26129866
)
Interacting Genes
5 interacting genes:
BRCA1
CRYAB
LMCD1
NGRN
PRKAA1
67 interacting genes:
ABI2
ACACA
BHLHE40
CAB39
CAMKK1
CDX4
CFTR
CHEK1
CRTC2
CTBP1
DVL2
EEF2K
EPM2A
FANCA
FNIP1
GATA1
GOLGA2
GRIK2
HDAC5
HMBOX1
HOMEZ
IKZF3
INO80E
KIF16B
KRT40
L3MBTL3
MDM4
MORC4
MTOR
MTUS2
PASK
PFKFB2
PHC2
PNMA5
PPM1A
PPM1E
PPM1F
PPP2CA
PRKAB1
PRKAB2
PRKAG1
PRKAG3
PSMD11
RACK1
RAD54B
RAF1
RBPMS
RFX6
RIMBP3
ROPN1
RPTOR
SRPK2
SSX2IP
STK11
THAP1
TLE5
TOMM34
TRIM27
TRIP6
TSC2
TSC22D4
TXNIP
UBXN11
ULK1
VPS37B
VPS52
ZBED1
Entrez ID
53632
5562
HPRD ID
16085
04115
Ensembl ID
ENSG00000115592
ENSG00000132356
Uniprot IDs
Q9UGI9
Q13131
PDB IDs
4RED
4RER
4REW
5EZV
6C9F
6C9G
6C9H
6C9J
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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