PRKAG3 and LMCD1

Number of citations of the paper that reports this interaction (PubMedID 19616115)
10

Data Source:
BioGRID (two hybrid)

		PRKAG3	LMCD1
Description		protein kinase AMP-activated non-catalytic subunit gamma 3	LIM and cysteine rich domains 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytosol Nucleotide-activated Protein Kinase Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding	Transcription Corepressor Activity Zinc Ion Binding
	Biological Process	Glycogen Biosynthetic Process Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Macroautophagy Regulation Of Macroautophagy Intracellular Signal Transduction Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cardiac Muscle Hypertrophy Cellular Protein Metabolic Process Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs	Surfactant metabolism
Drugs		Acetylsalicylic acid
Diseases
GWAS		HDL cholesterol ( 25961943) Male-pattern baldness ( 28196072)	Brain volume in infants (intracranial brain volume) ( 28763065) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Low high density lipoprotein cholesterol levels ( 26879886) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Rumination (response to stress) ( 30886212) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		5 interacting genes: BRCA1 CRYAB LMCD1 NGRN PRKAA1	7 interacting genes: APP FBXO25 IKBKG NKX3-1 PRKAG3 TRIM55 TRIM63
Entrez ID		53632	29995
HPRD ID		16085	06891
Ensembl ID		ENSG00000115592	ENSG00000071282
Uniprot IDs		Q9UGI9	B4DEY6 B7Z6R5 H7C3D2 Q9NZU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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