PKNOX1 and HOXB6

Number of citations of the paper that reports this interaction (PubMedID 7729685)
128

Data Source:
HPRD (in vivo)

		PKNOX1	HOXB6
Description		PBX/knotted 1 homeobox 1	homeobox B6
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex Cytoplasm	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding
	Biological Process	Angiogenesis Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Childhood body mass index ( 26604143)
Interacting Genes		16 interacting genes: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 PCNT POU2F1 RFX3 TLX1 VPS37C ZBTB3	12 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 HOXB7 KRT15 PKNOX1 PLSCR1 SAT1 TCEAL1 TCF21
Entrez ID		5316	3216
HPRD ID		03653	00849
Ensembl ID		ENSG00000160199	ENSG00000108511
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	P17509
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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