PGM1 and S100A1

Number of citations of the paper that reports this interaction (PubMedID 8894274)
7

Data Source:
HPRD (in vitro)

		PGM1	S100A1
Description		phosphoglucomutase 1	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Neutrophil Degranulation	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis
Pathways		Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation	Regulation of TLR by endogenous ligand
Drugs		Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate	Olopatadine
Diseases
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 19430480)
Interacting Genes		12 interacting genes: APP HSPB2 NLRP3 PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		5236	6271
HPRD ID		01389	01489
Ensembl ID		ENSG00000079739	ENSG00000160678
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	A0A0S2Z4H2 P23297
PDB IDs		5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6BJ0	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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