S100A1 and ANXA6

Number of citations of the paper that reports this interaction (PubMedID 9883272)
8

Data Source:
HPRD (in vitro)

		S100A1	ANXA6
Description		S100 calcium binding protein A1	annexin A6
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection	Cytoplasm Mitochondrion Lysosomal Membrane Focal Adhesion Membrane Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding	Phosphatidylserine Binding Calcium Channel Activity Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Ion Channel Activity Cholesterol Binding Chondroitin Sulfate Binding Identical Protein Binding Calcium-dependent Protein Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis	Neural Crest Cell Migration Plasma Membrane Repair Growth Plate Cartilage Chondrocyte Differentiation Regulation Of Muscle Contraction Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Apoptotic Signaling Pathway
Pathways		Regulation of TLR by endogenous ligand	Smooth Muscle Contraction
Drugs		Olopatadine
Diseases
GWAS			Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 25574825) Psoriatic arthritis ( 26626624)
Interacting Genes		27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1	14 interacting genes: A2M CDC73 CR2 ERBB2 LMNA MLH1 MTNR1B RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52
Entrez ID		6271	309
HPRD ID		01489	00231
Ensembl ID		ENSG00000160678	ENSG00000197043
Uniprot IDs		A0A0S2Z4H2 P23297	A0A0S2Z2Z6 P08133
PDB IDs		2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89	1M9I
Enriched GO Terms of Interacting Partners?
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