RAPGEF6 and RAP1A

  • Number of citations of the paper that reports this interaction (PubMedID 12581858)
  • 20
  • Data Source:
  • HPRD (in vivo, in vitro)

RAPGEF6

RAP1A

Description Rap guanine nucleotide exchange factor 6 RAP1A, member of RAS oncogene family
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • Crohn's disease ( 28067908)
  • Diisocyanate-induced asthma ( 25918132)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Perceived unattractiveness to mosquitoes ( 28199695)
  • Subjective well-being ( 27089181)
  • Ulcerative colitis ( 28067908)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Crohn's disease ( 30500874)
  • High altitude adaptation ( 28373541)
  • Osteoporosis-related phenotypes ( 20548944)
Interacting Genes 8 interacting genes: ABCA1 LINC00839 MRAS NEDD4 PTPN13 RAP1A RAP2A YWHAG 43 interacting genes: AFDN APBB1IP ARHGEF1 BIN1 BMX BRAF ELOA FADD FAF1 FAS GABARAPL2 GANAB HDAC1 HSPA1A HSPA4 KRIT1 MTNR1A NTRK1 PDE6D PPP2R1A PRKACA RABAC1 RAF1 RALGDS RAP1GAP RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASA1 RASA3 RASGRP2 RASGRP4 RASIP1 RGL4 RGS14 RUNDC3A SMARCA2 SMARCA4 TNFRSF10C
Entrez ID 51735 5906
HPRD ID 11483 01545
Ensembl ID ENSG00000158987 ENSG00000116473
Uniprot IDs B2RTU6 Q8TEU7 A8KAH9 P62834
PDB IDs 2D93 3LNY 1C1Y 1GUA 3KUC 4KVG
Enriched GO Terms of Interacting Partners?
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