RAP1A and RAPGEF5

  • Number of citations of the paper that reports this interaction (PubMedID 10934204)
  • 39
  • Data Source:
  • HPRD (in vitro)

RAP1A

RAPGEF5

Description RAP1A, member of RAS oncogene family Rap guanine nucleotide exchange factor 5
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Crohn's disease ( 30500874)
  • High altitude adaptation ( 28373541)
  • Osteoporosis-related phenotypes ( 20548944)
  • Depression in smokers ( 30219690)
  • Dialysis-related mortality ( 21546767)
  • Diastolic blood pressure ( 30224653)
  • Glaucoma ( 30104761)
  • Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699)
  • Night sleep phenotypes ( 27126917)
  • Spatial processing ( 31596458)
  • Squamous cell lung carcinoma ( 28604730)
  • Thyroid stimulating hormone levels ( 17903292)
Interacting Genes 43 interacting genes: AFDN APBB1IP ARHGEF1 BIN1 BMX BRAF ELOA FADD FAF1 FAS GABARAPL2 GANAB HDAC1 HSPA1A HSPA4 KRIT1 MTNR1A NTRK1 PDE6D PPP2R1A PRKACA RABAC1 RAF1 RALGDS RAP1GAP RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASA1 RASA3 RASGRP2 RASGRP4 RASIP1 RGL4 RGS14 RUNDC3A SMARCA2 SMARCA4 TNFRSF10C 7 interacting genes: MRAS PLAC9 RAP1A RAP2A RAP2B TMEM253 VANGL1
Entrez ID 5906 9771
HPRD ID 01545 15208
Ensembl ID ENSG00000116473 ENSG00000136237
Uniprot IDs A8KAH9 P62834 A8MQ07 Q5JPD2 Q92565
PDB IDs 1C1Y 1GUA 3KUC 4KVG 1WGY
Enriched GO Terms of Interacting Partners?
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