RNF181 and BTG1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RNF181	BTG1
Description		ring finger protein 181	BTG anti-proliferation factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coregulator Activity Protein Binding Enzyme Binding Kinase Binding
	Biological Process	Protein Ubiquitination Protein Autoubiquitination	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Cell Migration Negative Regulation Of Cell Growth Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Fibroblast Apoptotic Process
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)	Heart failure ( 20445134) Metabolite levels ( 23823483) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		22 interacting genes: BCL10 BIRC2 BTG1 CARD11 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U VPS11 ZMYND10	13 interacting genes: CCNA2 CDKN2D CNOT7 CNOT8 HOXB9 PRMT1 RARA RNF181 SKP2 THRA THRB TUBA1A XRCC6
Entrez ID		51255	694
HPRD ID		14236	15912
Ensembl ID		ENSG00000168894	ENSG00000133639
Uniprot IDs		Q9P0P0	P62324 Q6IBC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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