PCSK5 and PTPRM

  • Number of citations of the paper that reports this interaction (PubMedID 8620001)
  • 19
  • Data Source:
  • HPRD (in vitro)

PCSK5

PTPRM

Description proprotein convertase subtilisin/kexin type 5 protein tyrosine phosphatase receptor type M
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease progression score ( 29860282)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Ankylosing spondylitis ( 30946743)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Diverticular disease ( 30177863)
  • Glucocorticoid-induced osteonecrosis ( 26265699)
  • Glucose homeostasis traits ( 25524916)
  • Height ( 28552196 20881960 25282103 23563607 31562340)
  • Inflammatory bowel disease ( 27569725)
  • Intraocular pressure ( 29785010 31959993 30054594)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lead levels ( 26025379)
  • Male fertility ( 22633400)
  • Metabolite levels (5-HIAA) ( 23319000)
  • Pursuit maintenance gain ( 29064472)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Systemic sclerosis ( 30247649)
  • Takayasu arteritis ( 25604533)
  • Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
  • Vascular brain injury ( 25188341)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Dialysis-related mortality ( 21546767)
  • Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
  • Glucose homeostasis traits ( 25524916)
  • Hippocampal volume ( 29860282)
  • Huntington's disease progression ( 28642124)
  • Iris heterochromicity ( 30895295)
  • Lateral ventricle temporal horn volume ( 31530798)
  • Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828)
  • Recurrence of mild malaria attacks ( 31667592)
  • Response to methotrexate in rheumatoid arthritis ( 24583629)
  • Sitting height ratio ( 25865494)
Interacting Genes 19 interacting genes: AMH APPBP2 ATN1 CACNA1A GLRX3 ITGA6 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 KRTAP5-9 LCE3C MEOX2 NOTCH2NLA NUFIP2 PMCH PTPRM REN STK16 11 interacting genes: BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1
Entrez ID 5125 5797
HPRD ID 08985 01479
Ensembl ID ENSG00000099139 ENSG00000173482
Uniprot IDs Q92824 P28827
PDB IDs 1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?