ZNF219 and LMO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF219	LMO1
Description		zinc finger protein 219	LIM domain only 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Integral Component Of Membrane	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Histamine Receptor Activity Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Neurotransmitter Levels Transcription, DNA-templated Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Chondrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Limb Bud Formation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Resting heart rate ( 27798624)	Alcohol consumption ( 23743675) Body mass index ( 31888951 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Diastolic blood pressure ( 27618447) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Height ( 31562340) Neuroblastoma ( 22941191 21124317) Offspring birth weight ( 31043758) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 27618447)
Interacting Genes		11 interacting genes: BCL2L1 CDK4 CSNK2A2 CTBP1 LMO1 MAPK3 MAPK8 SH3GL2 SH3KBP1 SUFU TTC32	39 interacting genes: ADAMTSL4 BCL11A BLZF1 CARD9 CBY2 CDCA7L CDX4 CEP170P1 CEP44 ERBIN GABPB1 GATA3 GOLGA2 IKZF3 KANK2 KRT40 LDB1 LPXN LYL1 LZTS2 NAGK NHLH1 NUTM1 PHC2 PTPN3 RBBP8 REL SAXO1 SNTA1 SOX5 TAL1 TAL2 TASOR2 TCF4 TFIP11 TLE5 TRIM27 ZBTB43 ZNF219
Entrez ID		51222	4004
HPRD ID		05435	01738
Ensembl ID		ENSG00000165804	ENSG00000166407
Uniprot IDs		Q9P2Y4	E9PK83 P25800
PDB IDs
Enriched GO Terms of Interacting Partners?
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