CHCHD2 and INCA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CHCHD2	INCA1
Description		coiled-coil-helix-coiled-coil-helix domain containing 2	inhibitor of CDK, cyclin A1 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Intermembrane Space	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Binding Transcription Factor Binding Sequence-specific DNA Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding
	Biological Process	Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Hypoxia	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Metabolite levels ( 23823483 31628463) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)	Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: ADAMTSL4 EHMT2 FBXO7 GOLGA2 IKZF3 INCA1 KRT31 KRT40 LHX4 REL TCF4 TREX1 TRIM54	39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1
Entrez ID		51142	388324
HPRD ID		09879	17150
Ensembl ID		ENSG00000106153	ENSG00000196388
Uniprot IDs		Q9Y6H1	Q0VD86
PDB IDs
Enriched GO Terms of Interacting Partners?
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