PCMT1 and AIMP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PCMT1	AIMP2
Description		protein-L-isoaspartate (D-aspartate) O-methyltransferase	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome Extracellular Vesicle	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding Cadherin Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Protein Methylation Protein Repair	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity
Pathways		Protein repair	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS			Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		7 interacting genes: AIMP2 APOA1 APOE CHD3 CREBBP RPIA VKORC1	48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		5110	7965
HPRD ID		08908	02915
Ensembl ID		ENSG00000120265	ENSG00000106305
Uniprot IDs		A0A0A0MRJ6 A0A3F2YNX8 B7Z972 F6S8N6 H7BY58 P22061	A0A024QZY1 A8MU58 Q13155
PDB IDs		1I1N 1KR5	4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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