DEF6 and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		DEF6	HOMEZ
Description		DEF6 guanine nucleotide exchange factor	homeobox and leucine zipper encoding
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 18391951) Systemic lupus erythematosus ( 28714469)	Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		15 interacting genes: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70	37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688
Entrez ID		50619	57594
HPRD ID		10869	12167
Ensembl ID		ENSG00000023892	ENSG00000215271
Uniprot IDs		Q9H4E7	Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?