ATP2A2 and IRS2

  • Number of citations of the paper that reports this interaction (PubMedID 9295312)
  • 12
  • Data Source:
  • HPRD (in vitro, in vivo)

ATP2A2

IRS2

Description ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 insulin receptor substrate 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Glucose homeostasis traits ( 25524916)
  • Protein quantitative trait loci ( 18464913)
  • QT interval ( 24952745)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Waist circumference ( 28552196)
Interacting Genes 10 interacting genes: BCL2 CAMK2A HGS IRS1 IRS2 MDM2 PLN S100A1 SPP1 TRIM14 40 interacting genes: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL MTDH NEDD4 NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID 488 8660
HPRD ID 00161 02878
Ensembl ID ENSG00000174437 ENSG00000185950
Uniprot IDs A0A0S2Z3L2 P16615 Q9P084 Q9Y4H2
PDB IDs 5ZTF 6JJU 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
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