NHLH1 and LMO1

Number of citations of the paper that reports this interaction (PubMedID 10603358)
8

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		NHLH1	LMO1
Description		nescient helix-loop-helix 1	LIM domain only 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Dimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675) Body mass index ( 31888951 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Diastolic blood pressure ( 27618447) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Height ( 31562340) Neuroblastoma ( 22941191 21124317) Offspring birth weight ( 31043758) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 27618447)
Interacting Genes		10 interacting genes: CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3	39 interacting genes: ADAMTSL4 BCL11A BLZF1 CARD9 CBY2 CDCA7L CDX4 CEP170P1 CEP44 ERBIN GABPB1 GATA3 GOLGA2 IKZF3 KANK2 KRT40 LDB1 LPXN LYL1 LZTS2 NAGK NHLH1 NUTM1 PHC2 PTPN3 RBBP8 REL SAXO1 SNTA1 SOX5 TAL1 TAL2 TASOR2 TCF4 TFIP11 TLE5 TRIM27 ZBTB43 ZNF219
Entrez ID		4807	4004
HPRD ID		01212	01738
Ensembl ID		ENSG00000171786	ENSG00000166407
Uniprot IDs		Q02575 Q5T203	E9PK83 P25800
PDB IDs
Enriched GO Terms of Interacting Partners?
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