NEK1 and KIF3A

Number of citations of the paper that reports this interaction (PubMedID 14690447)
27

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NEK1	KIF3A
Description		NIMA related kinase 1	kinesin family member 3A
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Centriolar Satellite	Cell Centrosome Centriole Cytosol Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Kinesin II Complex Extracellular Exosome Ciliary Tip Axon Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding 14-3-3 Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rab GTPase Binding Protein Phosphatase Binding Spectrin Binding
	Biological Process	Protein Phosphorylation Cell Cycle Regulation Of Mitotic Cell Cycle Peptidyl-tyrosine Phosphorylation Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity DNA Damage Response, Detection Of DNA Damage Cell Division Cilium Assembly	Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Organization Microtubule-based Movement Axon Guidance Anterograde Axonal Transport Centriole-centriole Cohesion Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Protein Localization To Cell Junction
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Hedgehog 'off' state Intraflagellar transport Activation of SMO Activation of SMO COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases		Short rib-polydactyly syndrome
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656) Supramarginal gyrus volume ( 31530798)	Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 25574825 22197932 26482879) Atopic march ( 26542096) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mosquito bite size ( 28199695)
Interacting Genes		18 interacting genes: ATRX CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD SIRPA TP53BP1 TSC2 YWHAH ZNF350	14 interacting genes: APP DISC1 GRB2 KIF3B KIF3C LIG4 MAP3K10 MAP3K11 NEK1 PLEKHA5 PPP1R15A RPGR TRIM14 VHL
Entrez ID		4750	11127
HPRD ID		06847	05250
Ensembl ID		ENSG00000137601	ENSG00000131437
Uniprot IDs		Q5JXL9 Q96PY6	B4DHG8 E9PES4 J3KPF9 Q05CT3 Q9Y496
PDB IDs		4APC 4B9D
Enriched GO Terms of Interacting Partners?
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