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NEK1

Description NIMA related kinase 1
Image
GO Annotations Cellular Component
  • Pericentriolar Material
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Centrosome
  • Cytosol
  • Centriolar Satellite
Molecular Function
  • Protein Kinase Activity
  • Protein Serine/threonine Kinase Activity
  • Protein Tyrosine Kinase Activity
  • Protein Binding
  • ATP Binding
  • Kinase Activity
  • Metal Ion Binding
  • 14-3-3 Protein Binding
Biological Process
  • Protein Phosphorylation
  • Cell Cycle
  • Regulation Of Mitotic Cell Cycle
  • Peptidyl-tyrosine Phosphorylation
  • Signal Transduction By Protein Phosphorylation
  • Stress-activated Protein Kinase Signaling Cascade
  • Activation Of Protein Kinase Activity
  • DNA Damage Response, Detection Of DNA Damage
  • Cell Division
  • Cilium Assembly
Pathways
Drugs
Diseases
  • Short rib-polydactyly syndrome
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Night sleep phenotypes ( 27126917)
  • Schizophrenia ( 28991256 25056061 29483656)
  • Supramarginal gyrus volume ( 31530798)
Interacting Genes 18 interacting genes: ATRX CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD SIRPA TP53BP1 TSC2 YWHAH ZNF350
Entrez ID 4750
HPRD ID 06847
Ensembl ID ENSG00000137601
Uniprot IDs Q5JXL9 Q96PY6
PDB IDs 4APC 4B9D
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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