NELL1 and ATN1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NELL1	ATN1
Description		neural EGFL like 1	atrophin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nuclear Envelope Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase C Binding Calcium Ion Binding Protein Binding Heparin Binding	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Nervous System Development Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Bone Mineralization Negative Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cellular Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process
Pathways			Regulation of PTEN gene transcription
Drugs
Diseases			Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Attention function in attention deficit hyperactive disorder ( 26174813) Blood protein levels ( 30072576 29875488) Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia ( 29266176) Cannabis use (initiation) ( 22823124) Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Crohn's disease ( 17684544) Fibrinogen levels (smoking status, alcohol consumption or body mass index interaction) ( 25551457) Hepcidin levels ( 27846281) Hepcidin/transferrin saturation ratio ( 27846281) Hippocampal sclerosis ( 25188341) Methadone dose in opioid dependence ( 28115739) Obesity-related traits ( 23251661) Prudent dietary pattern ( 28644415) Response to amphetamines ( 22952603) Response to long-chain n-3 polyunsaturated fatty acid supplementation (change in triglyceride levels) ( 24847101) Weight ( 28552196)
Interacting Genes		4 interacting genes: ATN1 ATXN7 CACNA1A GFI1B	93 interacting genes: AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPOP STXBP4 SYVN1 TEP1 TLE1 TLE5 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		4745	1822
HPRD ID		09081	06311
Ensembl ID		ENSG00000165973	ENSG00000111676
Uniprot IDs		B3KXR2 F5H6I3 J3KNC5 K9UUD5 Q92832	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?
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