ATN1 and LTBP4

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	LTBP4
Description		atrophin 1	latent transforming growth factor beta binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Transforming Growth Factor Beta-activated Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Glycosaminoglycan Binding Transforming Growth Factor Beta Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process	Regulation Of Cell Growth Protein Folding Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Proteolysis Growth Hormone Secretion Regulation Of Cell Differentiation
Pathways		Regulation of PTEN gene transcription	Molecules associated with elastic fibres
Drugs
Diseases		Dentatorubropallidoluysian atrophy (DRPLA)	Cutis laxa with severe pulmonary, gastrointestinal, and urinary abnormalities; Urban-Rifkin-Davis syndrome
GWAS			Lung function (FEV1/FVC) ( 26635082 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		93 interacting genes: AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPOP STXBP4 SYVN1 TEP1 TLE1 TLE5 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	11 interacting genes: ATN1 ATXN7 CACNA1A CRKL CRY1 FBLN1 FRAT1 GFI1B ITSN2 RAC1 TGFB1
Entrez ID		1822	8425
HPRD ID		06311	05274
Ensembl ID		ENSG00000111676	ENSG00000090006
Uniprot IDs		P54259 Q86V38	A0A0C4DH07 B3KXY6 Q8N2S1
PDB IDs
Enriched GO Terms of Interacting Partners?
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