NEDD9 and DMRTB1

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		NEDD9	DMRTB1
Description		neural precursor cell expressed, developmentally down-regulated 9	DMRT like family B with proline rich C-terminal 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytosol Plasma Membrane Focal Adhesion Cell Cortex Lamellipodium	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Cell Cycle Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Regulation Of Growth Actin Filament Bundle Assembly Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Actin Filament Reorganization Activation Of GTPase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Childhood dental caries in permanent teeth ( 29931343) Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) HIV-1 susceptibility ( 22174851) Macular thickness ( 30535121) Prostate cancer ( 25217961) Small cell lung carcinoma ( 28604730)	Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)
Interacting Genes		45 interacting genes: ABL1 APP AURKA BANP BCAR1 BCAR3 CDH1 CHAT CRK CRKL DIMT1 DMRTB1 ELSPBP1 FYN FZR1 ID2 ITCH LCK LYN MICAL1 NAB2 NCK1 NFKBIA NOTCH3 PIK3CA PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 TCF3 TFCP2 TRIM27 TRIP6 ZNF318 ZYX	30 interacting genes: C1orf94 CCND3 CDKN2D CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EYA2 FXR2 HNRNPUL1 IL16 LENG8 NCKIPSD NEDD9 NIF3L1 PARD6G PEF1 PKP2 PRMT2 QKI RBFOX1 RBFOX2 RBM14 RBPMS RPA2 SLAIN1 SORBS3 TSG101 VASP
Entrez ID		4739	63948
HPRD ID		11888	16828
Ensembl ID		ENSG00000111859	ENSG00000143006
Uniprot IDs		A0A024QZV9 A0A087WUD2 Q14511	I6L9A0 Q96MA1
PDB IDs		2L81 5X3S
Enriched GO Terms of Interacting Partners?
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