NCL and S100A11

Number of citations of the paper that reports this interaction (PubMedID 14623863)
31

Data Source:
HPRD (in vitro, in vivo)

		NCL	S100A11
Description		nucleolin	S100 calcium binding protein A11
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Ruffle Extracellular Region Extracellular Space Nucleus Cytoplasm Adherens Junction Secretory Granule Lumen Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Angiogenesis Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Proliferation Positive Regulation Of Smooth Muscle Cell Migration Neutrophil Degranulation Cell-cell Adhesion
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Neutrophil degranulation
Drugs			Phosphonothreonine
Diseases
GWAS		Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Height ( 31562340) Noise-induced hearing loss ( 26121033)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Male-pattern baldness ( 28196072)
Interacting Genes		53 interacting genes: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689	5 interacting genes: ACTB ANXA1 CEP20 NCL S100B
Entrez ID		4691	6282
HPRD ID		01245	04385
Ensembl ID		ENSG00000115053	ENSG00000163191
Uniprot IDs		B3KM80 P19338	P31949 V9HWH9
PDB IDs		2FC8 2FC9 2KRR	1V4Z 1V50 2LUC
Enriched GO Terms of Interacting Partners?
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