S100A11 and S100B

Number of citations of the paper that reports this interaction (PubMedID 10913138)
20

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		S100A11	S100B
Description		S100 calcium binding protein A11	S100 calcium binding protein B
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Cytoplasm Adherens Junction Secretory Granule Lumen Extracellular Exosome	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Proliferation Positive Regulation Of Smooth Muscle Cell Migration Neutrophil Degranulation Cell-cell Adhesion	Axonogenesis Central Nervous System Development Learning Or Memory Memory Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Myelination Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Neuronal Synaptic Plasticity Astrocyte Differentiation Response To Glucocorticoid Response To Methylmercury Long-term Synaptic Potentiation Cellular Response To Hypoxia Negative Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Neutrophil degranulation	Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Phosphonothreonine	Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium Citrate Calcium Phosphate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Male-pattern baldness ( 28196072)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)
Interacting Genes		5 interacting genes: ACTB ANXA1 CEP20 NCL S100B	42 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PCNT PGM1 RABAC1 S100A1 S100A11 S100A2 S100A6 S100P SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1
Entrez ID		6282	6285
HPRD ID		04385	01505
Ensembl ID		ENSG00000163191	ENSG00000160307
Uniprot IDs		P31949 V9HWH9	A0A0S2Z4C5 P04271
PDB IDs		1V4Z 1V50 2LUC	1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F
Enriched GO Terms of Interacting Partners?
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